bvdv induced gastro-neuropathy outbreak in a feedlot calves around tehran (iran)
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abstract
an outbreak of a lethal disease was reported in 4–6-month-old holstein calves in a feedlot around tehran. the signs of central nervous system and gastrointestinal system (gi) involvement were observed in the diseased animals. necropsy samples of gi, liver, kidney, spleen and lung from 3 died animals were prepared for histopathological examination. blood and formalin-fixed ear notch samples of 6 calves were submitted for rt-pcr, antigen-capture elisa (ace) and immunohistochemistry (ihc) for the detection of bvdv. the results of ace on buffy coats were negative but rt-pcr of all 6 cases and ihc of 4 cases were positive for bvdv infection. based on the clinical signs and pathological findings in the gi system and brain, we strongly suggest that the bvdv may represent a gastro-neuropathogen strain. to the best of our knowledge, this is the first outbreak of gastro-neuropathogenic bvdv infection in iran, which may be acquired postnatally.
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Journal title:
iranian journal of veterinary researchPublisher: shiraz university
ISSN 1728-1997
volume 9
issue 3 2008
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